Endocrine Abstracts

Introduction: Polycystic ovary syndrome (PCOS) is a heterogeneous disorder, characterized by chronic anovulation and hyperandrogenism. Hirsutism, defined as excessive terminal hair that appears in a male pattern in a woman, is frequently present in patients with PCOS. We aimed to determine the clinical and biological characteristics of hirsute patients with PCOS.Methods: It was a retrospective study included 30 women diagnosed with PCOS according to the ...

Introduction: The reactive pituitary gland enlargement is a non-neoplastic growth of at least one pituitary lineage, which can often be essential or secondary to prolonged deficit of a gland target. It may be difficult to differentiate from functional pituitary adenomas. Herein we report a case of pituitary hyperplasia secondary to congenital primary hypothyroidism diagnosed at the age of 38 years.Observation: A 38-year-old female patient presented with ...

Introduction: Myasthenia gravis is an autoimmune neuromuscular disease characterized by the presence of anti-acetylcholine receptor antibodies. It can be isolated or associated with other auto-immune conditions. Graves’ disease is an autoimmune disorder typically characterized by the presence of circulating autoantibodies that tie to and stimulate the thyroid hormone receptor. Coexisting myasthenia gravis and Graves’ disease is a rare but well recognized condition. T...

ObjectiveDescribe the clinical, paraclinical, etiological and therapeutic profile of adrenal incidentalomas.Material and methodsRetrospective study, conducted on 100 patients previously hospitalized in the endocrinology department of the university hospital center RABTA, following the fortuitous discovery of an adrenal mass over a period of 10 years.ResultsThe mea...

IntroductionThe insulin tolerance test (ITT) is the gold standard for the assessment of the integrity of the hyopothalamo-pituitray adrenal axis. it’s major drawbacks are the mandatory presence of an experienced physician and continuous supervision to detect any complication. Our study aims to evaluate the indications and the outcomes of the ITT performed in our department.Patients and methodsWe conducte...

IntroductionFahr’s syndrome (FS) is a rare neurodegenerative disorder. It’s characterized by abnormal calcifications in basal ganglia and cerebral cortex inducing neuropsychiatric disorders and cognitive impairment. The aim of our study was to assess the prevalence of FS, its characteristics, and its associated factors in patients with permanent hypoparathyroidism.MethodsWe conducted a cross-section...

IntroductionHomeostasis model assessment for insulin resistance (HOMA-IR) is widely used as a marker of insulin resistance. However, it reminds an expensive maker requiring insulin dosage. Several studies tried to found simple alternative predictors of insulin resistance such as triglycerides to HDL-C ratio with conflicting reported findings. The aim of our study was to investigate the usefulness of the atherogenic index of plasma (AIP) and the visceral ...

IntroductionNasopharyngeal carcinoma is characterized by distinct geographical distribution and is particularly prevalent in East and Southeast Asia. Environmental factors, genetic structure, and Epstein Barr virus infection are involved in the etiology of the disease. While nasal and otological symptoms are the most common (80%), intracranial extension is prevalent among 8% of cases and pituitary localization is rarely described in the literature. We re...

IntroductionPrimary mediastinal goiter is an extremely uncommon entity. The majority of primary mediastinal goiters were reported as incidental findings on chest imaging of asymptomatic patients. Symptoms related to compression of adjacent structures and hyperthyroidism were rarely described. Herein we report a case of subclinical hyperthyroidism secondary to a primary mediastinal goiter.ObservationA 50 year-...

Hashimoto’s thyroiditis (HT) is a chronic disease that needs a daily substitution by thyroid hormones. The purpose of this study was to assess the level of therapeutic adherence to the hormonal treatment in HT patients and its impact on the thyroid function control.MethodsIt is a cross sectional study including 43 patients treated for hypothyroid Hashimoto’s thyroiditis by levothyroxine (LT4). The patient adherence to tre...